SECTION 2. HAZARDS IDENTIFICATION

2.1 Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Acute toxicity, Oral (Category 3), H301
Acute toxicity, Inhalation (Category 2), H330
Acute toxicity, Dermal (Category 3), H311
Skin corrosion (Category 1A), H314
Serious eye damage (Category 1), H318
Respiratory sensitisation (Category 1), H334
Skin sensitisation (Category 1), H317
Carcinogenicity (Category 2), H351
Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335

2.2 GHS Label elements, including precautionary statements

Pictogram
Signal word Danger
Hazard statement(s)
H301 + H311 Toxic if swallowed or in contact with skin
H314 Causes severe skin burns and eye damage.
H317 May cause an allergic skin reaction.
H318 Causes serious eye damage.
H330 Fatal if inhaled.
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H335 May cause respiratory irritation.
H351 Suspected of causing cancer.
Precautionary statement(s)
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and
understood.
P260 Do not breathe dust/ fume/ gas/ mist/ Vapors/ spray.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection.
P284 Wear respiratory protection.
P301 + P310 + P330 IF SWALLOWED: Immediately call a POISON CENTER or doctor/
physician. Rinse mouth.
P301 + P330 + P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing.
Rinse skin with water/shower.
P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for
breathing. Immediately call a POISON CENTER or doctor/ physician.
P305 + P351 + P338 + P310 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. Immediately
call a POISON CENTER or doctor/ physician.
P308 + P313 IF exposed or concerned: Get medical advice/ attention.
P333 + P313 If skin irritation or rash occurs: Get medical advice/ attention.
P362 Take off contaminated clothing and wash before reuse.
P403 + P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal plant.
2.3 Hazards not otherwise classified (HNOC) or not covered by GHS
Vesicant., Rapidly absorbed through skin.

SECTION 3. COMPOSITION/INFORMATION ON INGREDIENTS

3.1 Substances
Synonyms : Methyl iodide
Formula : CH3I
Molecular weight : 141.94 g/mol
CAS-No. : 74-88-4
EC-No. : 200-819-5
Index-No. : 602-005-00-9
Hazardous components
Component Classification Concentration
Methyl iodide
Acute Tox. 3; Acute Tox. 2;
Acute Tox. 3; Skin Corr. 1A;
Eye Dam. 1; Resp. Sens. 1;
Skin Sens. 1; Carc. 2; STOT
SE 3; H301 + H311, H314,
H317, H330, H334, H335,
H351
<= 100 %

SECTION 4. FIRST AID MEASURES

4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.Move out of dangerous area.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Take victim
immediately to hospital. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.Continue rinsing eyes during
transport to hospital.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a
physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available

SECTION 5. FIREFIGHTING MEASURES

5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
No data available
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information
No data available

SECTION 6. ACCIDENTAL RELEASE MEASURES

6.1 Personal precautions, protective equipment and emergency procedures
Wear respiratory protection. Avoid breathing Vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel
to safe areas.
For personal protection see section 8.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for
disposal.
6.4 Reference to other sections
For disposal see section 13.

SECTION 7. HANDLING AND STORAGE

7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid inhalation of Vapor or mist.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully
resealed and kept upright to prevent leakage.
Recommended storage temperature 2 - 8 °C
Light sensitive. Moisture sensitive.
Storage class (TRGS 510): Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8. EXPOSURE CONTROLS/PERSONAL PROTECTION

8.1 Control parameters
Components with workplace control parameters
Component CAS-No. Value Control
parameters
Basis
Methyl iodide 74-88-4 TWA 2.000000 ppm
USA. ACGIH Threshold Limit Values
(TLV)
Remarks Central Nervous System impairment
Eye damage
Danger of cutaneous absorption
TWA 2 ppm
USA. ACGIH Threshold Limit Values
(TLV)
Central Nervous System impairment
Eye damage
Danger of cutaneous absorption
TWA 5.000000 ppm
28.000000
mg/m3
USA. Occupational Exposure Limits
(OSHA) - Table Z-1 Limits for Air
Contaminants
Skin designation
The value in mg/m3 is approximate.
TWA 2.000000 ppm
10.000000
mg/m3
USA. NIOSH Recommended
Exposure Limits
Potential Occupational Carcinogen
See Appendix A
Potential for dermal absorption
8.2 Exposure controls
Appropriate engineering controls
Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.
Personal protective equipment
Eye/face protection
Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection tested and
approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without
touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after
use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
Full contact
Material: Fluorinated rubber
Minimum layer thickness: 0.7 mm
Break through time: > 480 min
Material tested:Vitoject® (KCL 890 / Aldrich Z677698, Size M)
Splash contact
Material: Fluorinated rubber
Minimum layer thickness: 0.7 mm
Break through time: > 480 min
Material tested:Vitoject® (KCL 890 / Aldrich Z677698, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method:
EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the
supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an
industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It
should not be construed as offering an approval for any specific use scenario.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected according to
the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multipurpose
combination (US) or type AXBEK (EN 14387) respirator cartridges as a backup to engineering
controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators
and components tested and approved under appropriate government standards such as NIOSH (US) or CEN
(EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES

9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid
b) Odor No data available
c) Odor Threshold No data available
d) pH No data available
e) Melting point/freezing
point
Melting point/range: -64 °C (-83 °F) - lit.
f) Initial boiling point and
boiling range
41 - 43 °C (106 - 109 °F) - lit.
g) Flash point No data available
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower
flammability or
explosive limits
Upper explosion limit: 66 %(V)
Lower explosion limit: 8.5 %(V)
k) Vapor pressure 544 hPa (408 mmHg) at 20 °C (68 °F)
1,660 hPa (1,245 mmHg) at 55 °C (131 °F)
l) Vapor density 4.90 - (Air = 1.0)
m) Relative density 2.28 g/cm3 at 25 °C (77 °F)
n) Water solubility 14 g/l at 20 °C (68 °F)
o) Partition coefficient: noctanol/
water
log Pow: 1.5 at 20 °C (68 °F)
p) Auto-ignition
temperature
No data available
q) Decomposition
temperature
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
Relative Vapor density 4.90 - (Air = 1.0)

SECTION 10. STABILITY AND REACTIVITY

10.1 Reactivity
No data available
10.2 Chemical stability
Stable under recommended storage conditions.
Contains the following stabiliser(s):
Copper (100 ppm)
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
No data available
10.5 Incompatible materials
Strong oxidizing agents, Strong bases, Oxygen
10.6 Hazardous decomposition products
Other decomposition products - No data available
In the event of fire: see section 5

SECTION 11. TOXICOLOGICAL INFORMATION

11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - 76 mg/kg
LC50 Inhalation - Rat - 4 h - 1,300 mg/m3
LD50 Dermal - Guinea pig - 800 mg/kg
No data available
Skin corrosion/irritation
Skin - Rabbit
Result: Causes severe burns.
(Draize Test)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Risk of serious damage to eyes.
(Draize Test)
Respiratory or skin sensitisation
Germ cell mutagenicity
No data available
Carcinogenicity
This product is or contains a component that has been reported to be possibly carcinogenic based on its IARC, ACGIH,
NTP, or EPA classification.
Limited evidence of carcinogenicity in animal studies
IARC: 3 - Group 3: Not classifiable as to its carcinogenicity to humans (Methyl iodide)
ACGIH: No component of this product present at levels greater than or equal to 0.1% is identified as a
carcinogen or potential carcinogen by ACGIH.
NTP: No component of this product present at levels greater than or equal to 0.1% is identified as a
known or anticipated carcinogen by NTP.
OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as a
carcinogen or potential carcinogen by OSHA.
Reproductive toxicity
No data available
No data available
Specific target organ toxicity - single exposure
May cause respiratory irritation.
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
Additional Information
RTECS: Not available
Nausea, Dizziness, Headache, Blurred vision, Weakness, Drowsiness, Ataxia., Confusion., Convulsions, narcosis,
Pulmonary edema. Effects may be delayed., Symptoms of systemic copper poisoning may include: capillary damage,
headache, cold sweat, weak pulse, and kidney and liver damage, central nervous system excitation followed by
depression, jaundice, convulsions, paralysis, and coma. Death may occur from shock or renal failure. Chronic copper
poisoning is typified by hepatic cirrhosis, brain damage and demyelination, kidney defects, and copper deposition in the
cornea as exemplified by humans with Wilson's disease. It has also been reported that copper poisoning has lead to
hemolytic anemia and accelerates arteriosclerosis.
Nausea, Dizziness, Headache, Blurred vision, Weakness, Drowsiness, Ataxia., Confusion., Convulsions, narcosis,
Pulmonary edema. Effects may be delayed.
Stomach - Irregularities - Based on Human Evidence
Stomach - Irregularities - Based on Human Evidence

SECTION 12. ECOLOGICAL INFORMATION

12.1 Toxicity
No data available
12.2 Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Result: 16 % - Not readily biodegradable.
(Closed Bottle test)
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Other adverse effects
No data available

SECTION 13. DISPOSAL CONSIDERATIONS

13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste
disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a
chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.

SECTION 14. TRANSPORT INFORMATION

DOT (US)
UN number: 2644 Class: 6.1 Packing group: I
Proper shipping name: Methyl iodide
Reportable Quantity (RQ): 100 lbs
Poison Inhalation Hazard: Hazard zone B
IMDG
UN number: 2644 Class: 6.1 Packing group: I EMS-No: F-A, S-A
Proper shipping name: METHYL IODIDE
IATA
UN number: 2644 Class: 6.1
Proper shipping name: Methyl iodide
IATA Passenger: Not permitted for transport
IATA Cargo: Not permitted for transport

SECTION 15. REGULATORY INFORMATION

SARA 302 Components
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313 Components
The following components are subject to reporting levels established by SARA Title III, Section 313:
Methyl iodide
CAS-No.
74-88-4
Revision Date
2007-07-01
SARA 311/312 Hazards
Acute Health Hazard, Chronic Health Hazard
Massachusetts Right To Know Components
Methyl iodide
CAS-No.
74-88-4
Revision Date
2007-07-01
Pennsylvania Right To Know Components
Methyl iodide
CAS-No.
74-88-4
Revision Date
2007-07-01
Copper 7440-50-8 1989-08-11
New Jersey Right To Know Components
Methyl iodide
CAS-No.
74-88-4
Revision Date
2007-07-01
California Prop. 65 Components
WARNING! This product contains a chemical known to the
State of California to cause cancer.
Methyl iodide
CAS-No.
74-88-4
Revision Date
2007-09-28