SECTION 2. HAZARDS IDENTIFICATION
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Acute toxicity, Oral (Category 3), H301
Acute toxicity, Inhalation (Category 3), H331
Skin irritation (Category 2), H315
Serious eye damage (Category 1), H318
Respiratory sensitization (Category 1), H334
Skin sensitization (Category 1), H317
Carcinogenicity, Inhalation (Category 1B), H350i
Reproductive toxicity (Category 1B), H360
Specific target organ toxicity - repeated exposure, Inhalation (Category 1), Respiratory
Tract, H372
Signal word Danger
Hazard statement(s)
H301 + H331 Toxic if swallowed or if inhaled.
H315 Causes skin irritation.
H317 May cause an allergic skin reaction.
H318 Causes serious eye damage.
H334 May cause allergy or asthma symptoms or breathing difficulties
if inhaled.
H350i May cause cancer by inhalation.
H360 May damage fertility or the unborn child.
H372 Causes damage to organs (Respiratory Tract) through
prolonged or repeated exposure if inhaled.
Precautionary statement(s)
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and
understood.
P260 Do not breathe dust/ fume/ gas/ mist/ vapors/ spray.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P272 Contaminated work clothing must not be allowed out of the
workplace.
P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection.
P285 In case of inadequate ventilation wear respiratory protection.
P301 + P310 + P330 IF SWALLOWED: Immediately call a POISON CENTER/ doctor.
Rinse mouth.
P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 + P311 IF INHALED: Remove person to fresh air and keep comfortable
for breathing. Call a POISON CENTER/ doctor.
P305 + P351 + P338 +
P310
IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue
rinsing. Immediately call a POISON CENTER/ doctor.
P308 + P313 IF exposed or concerned: Get medical advice/ attention.
P333 + P313 If skin irritation or rash occurs: Get medical advice/ attention.
P362 Take off contaminated clothing and wash before reuse.
P403 + P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal
plant.
Hazards not otherwise classified (HNOC) or not covered by GHS
Strong hydrogen fluoride-releaser
SECTION 3. COMPOSITION/INFORMATION ON INGREDIENTS
Formula : F2Ni
Molecular weight : 96.69 g/mol
CAS-No. : 10028-18-9
EC-No. : 233-071-3
SECTION 4. FIRST AID MEASURES
Description of first-aid measures
General advice
Hydrofluoric (HF) acid burns require immediate and specialized first aid and medical
treatment. Symptoms may be delayed up to 24 hours depending on the concentration of
HF. After decontamination with water, further damage can occur due to
penetration/absorption of the fluoride ion. Treatment should be directed toward binding the
fluoride ion as well as the effects of exposure. Skin exposures can be treated with a 2.5%
calcium gluconate gel repeated until burning ceases. More serious skin exposures may
require subcutaneous calcium gluconate except for digital areas unless the physician is
experienced in this technique, due to the potential for tissue injury from increased
pressure. Absorption can readily occur through the subungual areas and should be
considered when undergoing decontamination. Prevention of absorption of the fluoride ion
in cases of ingestion can be obtained by giving milk, chewable calcium carbonate tablets or
Milk of Magnesia to conscious victims. Conditions such as hypocalcemia, hypomagnesemia
and cardiac arrhythmias should be monitored for, since they can occur after
exposure.Consult a physician. Show this material safety data sheet to the doctor in
attendance.Move out of dangerous area.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact
First treatment with calcium gluconate paste.Wash off with soap and plenty of water. Take
victim immediately to hospital. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a
physician.Continue rinsing eyes during transport to hospital.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult
a physician.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section
2.2) and/or in section 11
Indication of any immediate medical attention and special treatment needed
No data available
SECTION 5. FIREFIGHTING MEASURES
Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Hydrogen fluoride, Nickel/nickel oxides
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
SECTION 6. ACCIDENTAL RELEASE MEASURES
Personal precautions, protective equipment and emergency procedures
Wear respiratory protection. Avoid dust formation. Avoid breathing vapors, mist or gas.
Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
For personal protection see section 8.
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in
suitable, closed containers for disposal.
SECTION 7. HANDLING AND STORAGE
Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.Further processing
of solid materials may result in the formation of combustible dusts. The potential for
combustible dust formation should be taken into consideration before additional processing
occurs.
Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place.
Keep in a dry place. Do not store in glass Keep in a dry place.
Storage class (TRGS 510): 6.1D: Non-combustible, acute toxic Cat.3 / toxic hazardous
materials or hazardous materials causing chronic effects
SECTION 8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Appropriate engineering controls
Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately
after handling the product.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and
approved under appropriate government standards such as NIOSH (US) or EN
166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact
with this product. Dispose of contaminated gloves after use in accordance with
applicable laws and good laboratory practices. Wash and dry hands.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must
be selected according to the concentration and amount of the dangerous substance
at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a fullface
particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as
a backup to engineering controls. If the respirator is the sole means of protection,
use a full-face supplied air respirator. Use respirators and components tested and
approved under appropriate government standards such as NIOSH (US) or CEN
(EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance Form: powder
Odor odorless
Odor Threshold No data available
pH No data available
Melting point/freezing point No data available
Initial boiling point and boiling range No data available
Flash point ()Not applicable
Evaporation rate No data available
Flammability (solid, gas) The product is not flammable.
Upper/lower flammability or explosive limits No data available
Vapor pressure No data available
Vapor density No data available
Relative density 4.72 g/cm3 at 25 °C (77 °F)
Water solubility ca.40 g/l at 25 °C (77 °F) - soluble
Partition coefficient: n-octanol/water No data available
Autoignition temperature No data available
Decomposition temperature No data available
Viscosity No data available
Explosive properties No data available
Oxidizing properties No data available
SECTION 10. STABILITY AND REACTIVITY
Reactivity
No data available
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
No data available
Conditions to avoid
Reacts dangerously with glass.
Incompatible materials glass
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Hydrogen fluoride,
Nickel/nickel oxides
SECTION 11. TOXICOLOGICAL INFORMATION
Acute toxicity
LD50 Oral - Rat - female - 178 mg/kg
(OECD Test Guideline 425)
Inhalation: No data available
LD50 Dermal - Rat - male - > 100 mg/kg
Remarks: (ECHA)
No data available
Skin corrosion/irritation
Skin - Rabbit
Result: Irritating to skin. - 4 h
(OECD Test Guideline 404)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Causes serious eye damage.
(OECD Test Guideline 405)
Respiratory or skin sensitization
Maximization Test - Guinea pig
Result: positive
(OECD Test Guideline 406)
Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
May cause allergy or asthma symptoms or breathing difficulties if inhaled. Classified
according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Germ cell mutagenicity
Suspected of causing genetic defects.
In vitro mammalian cell gene mutation test
mouse lymphoma cells
Result: positive
OECD Test Guideline 474
Rat - male
Result: negative
Carcinogenicity
Positive evidence from human epidemiological studies (inhalation)
IARC: 3 - Group 3: Not classifiable as to its carcinogenicity to humans (Nickel(2+)
fluoride)
1 - Group 1: Carcinogenic to humans (Nickel(2+) fluoride)
NTP: No ingredient of this product present at levels greater than or equal to 0.1% is
identified as a known or anticipated carcinogen by NTP.
OSHA: No component of this product present at levels greater than or equal to 0.1% is
on OSHA’s list of regulated carcinogens.
Reproductive toxicity
May damage the unborn child.
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
Inhalation - Causes damage to organs through prolonged or repeated exposure. -
Respiratory Tract
Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Aspiration hazard
No data available
Additional Information
RTECS: QR6825000
Fluoride ion can reduce serum calcium levels possibly causing fatal hypocalcemia.
Salivation, Nausea, Vomiting, Fever, Dermatitis, Gastrointestinal disturbance, Material
reacts with moisture on the skin, eyes, and mucous membranes to generate hydrogen
fluoride. Hydrogen fluoride is extremely destructive and may cause deep progressive burns
that induce subcutaneous tissues to become blanched and bloodless resulting in lesions of
dead tissue that are slow to heal.
To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.
Stomach - Irregularities - Based on Human Evidence
Stomach - Irregularities - Based on Human Evidence
SECTION 12. ECOLOGICAL INFORMATION
Toxicity
Toxicity to fish semi-static test LC50 - Oncorhynchus mykiss (rainbow trout) - 15.3
mg/l - 96 h
Remarks: (ECHA)
Toxicity to daphnia
and other aquatic
invertebrates static test LC50 - Ceriodaphnia dubia (water flea) - 0.074 mg/l - 48h
(US-EPA)
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata - > 0.0815 - <
0.148 mg/l - 72 h
(OECD Test Guideline 201)
Toxicity to bacteria EC50 - activated sludge - 33 mg/l - 30 min
(ISO 8192)
Persistence and degradability
The methods for determining biodegradability are not applicable to inorganic substances.
Bioaccumulative potential
No data available
Mobility in soil
No data available
Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not
conducted
SECTION 13. DISPOSAL CONSIDERATIONS
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a
licensed professional waste disposal service to dispose of this material. Dissolve or mix
the material with a combustible solvent and burn in a chemical incinerator equipped with
an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.
SECTION 14. TRANSPORT INFORMATION
DOT (US)
UN number: 3288 Class: 6.1 Packing group: III
Proper shipping name: Toxic solid, inorganic, n.o.s. (Nickel(2+) fluoride)
Reportable Quantity (RQ):
Poison Inhalation Hazard: No
IMDG
UN number: 3288 Class: 6.1 Packing group: III EMS-No: F-A, S-A
Proper shipping name: TOXIC SOLID, INORGANIC, N.O.S. (Nickel(2+) fluoride)
Marine pollutant : yes
IATA
UN number: 3288 Class: 6.1 Packing group: III
Proper shipping name: Toxic solid, inorganic, n.o.s. (Nickel(2+) fluoride)
SECTION 15. REGULATORY INFORMATION
SARA 302 Components
This material does not contain any components with a section 302 EHS TPQ.
SARA 313 Components
The following components are subject to reporting levels established by SARA Title III,
Section 313:
Nickel(2+) fluoride
CAS-No.
10028-18-9
SARA 311/312 Hazards
Acute Health Hazard, Chronic Health Hazard
Massachusetts Right To Know Components
No components are subject to the Massachusetts Right to Know Act.
Pennsylvania Right To Know Components
Nickel(2+) fluoride CAS-No.
10028-18-9
